A sequential expression of a set of human genes occurs when a steroid molecule binds to the:
[AIPMT (Prelims)-2007]
(1) Ribosome (2) Transfer RNA (3) Messenger RNA (4) DNA sequence
Sol. Answer (4)
Please explain the following question and answer
Dear student.
The correct answer is 4. DNA sequence.
The correct answer is 4. DNA sequence.
The DNA sequence where a steroid receptor(molecule) binds is known as response elements. The binding is mediated by coactivators. The binding will cause a conformational change in the receptor proteins so that they can interact with additional transcription factors. This steroid receptor complex can regulate the expression of adjacent genes, which will induce a number of signalling pathways. The signalling pathway will activate the sequential expression of a set of human genes that carry response elements for that steroid receptors.
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